Fasting as a Path to Longevity: The Facts | Lifespan with Dr. David Sinclair - S2, Ep. 2

Eat less often. I can tell you that calorie restriction puts you in survival mode. There's a study that showed that you can slow down your rate of aging. That translates into a lower chance of mortality of between 10 and 15%. There's a lot of people worried about muscle. So, what does the science say? The

calorierestricted mice lived about 28% longer. LCA, which is a bile acid in the gut, could mimic [music] the anti-aging effects of calorie restriction. They changed the microbiome of the mice and calorie restriction [music] didn't work anymore. Welcome to Lifespan, a show where we discuss [music] the cuttingedge science of aging and how to

live healthier at any stage of life. I'm David Sinclair, a scientist and professor working on understanding why we age and discovering new ways to slow and even reverse the aging process. On this show, I share an insidider [music] look at the latest from my lab, the field, and what's just around the corner.

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Hey everyone, welcome back to Lifespan. The team and I went down many different investigative rabbit holes for this episode. One of the most interesting was food marketing and bad nutrition science. And it really made me realize how much of our struggle to keep our weight down is due to marketing, some of which goes back to the early 20th

century. So, we're going to talk about that in this show. And during the filming of this episode, I showed one of my most valued books from my collection. And I also shared something that really fascinates me. How a 50,000-year-old Neanderthal toebone fragment about the size of a large pee from a cave in