Sistema Gastrointestinal

Hello, good afternoon. In this seminar, we will address drugs that act by altering gastrointestinal function. We will discuss each of the health problems involved and the treatment we choose for those health problems. The topic we will cover this week is medications that affect gastrointestinal function. These are drugs used daily, as you would say in all

health centers, and for a wide variety of pathologies, which we will be looking at one by one. Therefore, you should know about these medications because, as I say, in your clinical practice, in your professional practice, you will be in continuous contact with this whole group of drugs. To get into the topic, the first thing we

have to explain, to try to understand, is the physiology of gastric secretion, which will be one of the points where we will try to intervene in the pharmacological treatment of this acid secretion. Yes, it is a complex, continuous process in which both central and peripheral factors contribute, all of which have the common goal of the secretion of hydrochloric acid

by the parietal cells of the stomach. Yes, in this diagram, here we see the stomach... The esophagus, the stomach with its parts: the cardia, which is the junction of the esophagus and the stomach; the fundus; the body; the antrum; and the pylorus. What you see here is the duodenum, the first and second

portions. And in the image next to it, we see the gastric mucosa with all its cells: the surface mucosal epithelium, which secretes mucus and bicarbonate; parietal cells, which are responsible for the secretion of hydrochloric acid and intrinsic factor; cells that are responsible for secreting somatostatin, a hormone that we will see what it